Queries 2

August 5, 2009 · Posted in Uncategorized · Comments Off 

Imperforate Anus


84 IMPERFORATE ANUS
Frederick M. Karrer M.D., Denis D. Bensard M.D.

1. What is imperforate anus?

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It is a congenital defect in which the opening of the anus is absent or misplaced, usually fistulizing anteriorly to the perineum or genitourinary (GU) tract. Anorectal malformations range from slight anterior malpositioning of the anus to complex cloacal deformities. Children with anorectal malformations commonly have other congenital anomalies, such as the VACTERL association.

Surgical Infectious Disease


15 SURGICAL INFECTIOUS DISEASE
Glenn W. Geelhoed M.D., M.P.H., DTMH

1. Have modern antibiotic developments controlled many, if not most, of the problems of surgical infection?

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No. In seriously ill surgical patients in intensive care unit (ICU) settings, the problems of sepsis have increased and remain among the principal causes of death in ICU patients, especially those with multiple organ failure and impairments of host defense. Antibiotic treatment may change the biographical sketch of the flora associated with patients’ deaths but cannot overcome the multiple causes of failing host resistance to infection that accompany barrier breeches to microbial invasion and the inflammatory and immunologic responses to the “usual suspects.”

Noninvasive Vascular Diagnostic Laboratory


73 NONINVASIVE VASCULAR DIAGNOSTIC LABORATORY
Darrell N. Jones Ph.D.

1. What is the role of the vascular diagnostic laboratory (VDL) in the assessment and treatment of patients with suspected vascular disease?